Rapidly Growing Mycobacteria (RGM) and Pacemaker Infection

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Infections due to rapidly growing mycobacteria.

Rapidly growing mycobacteria, generally of low virulence, are capable of causing a wide spectrum of infections. Increasing reports in the literature, referral center experiences, and data from the Infectious Disease Society of America Emerging Infectious Disease Network suggest that greater numbers of infections are occurring. Epidemiological study is imperative in understanding the true incide...

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Skin and Soft Tissue Infection due to Rapidly Growing Mycobacteria: Case Series and Literature Review

BACKGROUND Nontuberculous mycobacteria (NTM) are ubiquitous in soil and water. Most NTM cause disease in humans only rarely unless some aspect of host defense is impaired. Recently, rapidly growing mycobacteria (RGM) is not uncommon, and the prevalence of RGM infection has been increasing. RGM causes a wide spectrum of pulmonary and extrapulmonary diseases and has been shown as an important sou...

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In vitro activity of bedaquiline against rapidly growing nontuberculous mycobacteria

Bedaquiline (BDQ) has been proven to be effective in the treatment of multidrug-resistant tuberculosis. We hypothesized that BDQ could be a potential agent to treat nontuberculous mycobacterial (NTM) infection. The objective of this study was to evaluate the in vitro activity of BDQ against rapidly growing mycobacteria by assessing the minimal inhibitory concentration (MIC) and minimal bacteric...

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Antimicrobial susceptibility testing of rapidly growing mycobacteria isolated in Japan

BACKGROUND Difficult-to-treat infections caused by rapidly growing mycobacteria (RGM) are increasingly observed in clinical settings. However, studies on antimicrobial susceptibilities and effective treatments against RGM in Japan are limited. METHODS We conducted susceptibility testing of potential antimicrobial agents, including tigecycline and tebipenem, against RGM. Clinical RGM isolates ...

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National evaluation of rapidly growing mycobacteria outbreaks in Brazil

Methods A retrospective study was carried out by consulting the Agência Nacional de Vigilância Sanitária (ANVISA), Brazil, data system from January 1999 to December 2009. Additional data from private and public laboratories were also analyzed, including genotyping of a large group of RGM by means of Pulsed-field Gel Electrophoresis (PFGE). Cases were defined as confirmed, probable or suspect ac...

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ژورنال

عنوان ژورنال: Kansas Journal of Medicine

سال: 2011

ISSN: 1948-2035

DOI: 10.17161/kjm.v4i3.11381